Aging research, genomics, multiomics, 그리고 학술 연구 이야기
Predicting and interpreting cell-type-specific drug responses in the small-data regime using inductive priors Reem Alsulami, Robert Lehmann, Sumeer A. Khan, Vincenzo Lagani, Alberto Maillo, David Gomez-Cabrero, Narsis A. Kiani &...
Lifelong behavioral screen reveals an architecture of vertebrate aging Claire N. Bedbrook†, Ravi D. Nath†, Libby Zhang, Scott W. Linderman, Anne Brunet‡*, Karl Deisseroth‡* Science 391, eaea9795 (2026). DOI: 10.1126/science.aea9795...
논문 정보 Title: Predicting how perturbations reshape cellular trajectories with PerturbGen Authors: Kevin Chi Hao Ly, Adib Miraki Feriz, Tomoya Isobe, Amirhossein Vahidi, Delshad Vaghari, Anthony Rostron, … Muzlifah Haniffa,...
Heritability of intrinsic human life span is about 50% when confounding factors are addressed Ben Shenhar, Glen Pridham, Thaís Lopes De Oliveira, Naveh Raz, Yifan Yang, Joris Deelen, Sara Hägg,...
Li S, Hamaya R, Zhu H, Chen BH, Pereira AC, Ivey KL, Rist PM, Manson JE, Dong Y & Sesso HD. Effects of daily multivitamin–multimineral and cocoa extract supplementation on...
논문 정보 Title: Genome modelling and design across all domains of life with Evo 2 Authors: Garyk Brixi, Matthew G. Durrant, Jerome Ku, Michael Poli, Greg Brockman, Daniel Chang, Gabriel...
논문 정보 Title: Korean Genome Project: 1094 Korean personal genomes with clinical information Authors: Sungwon Jeon, Youngjune Bhak, Yeonsong Choi, Yeonsu Jeon, Seunghoon Kim, Jaeyoung Jang, Jinho Jang, Asta Blazyte,...
논문 정보 Title: Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery Authors: Anatoly Urban, Denis Sidorenko, Diana Zagirova,...
이 포스트는 Diffusion Model의 기본 이론을 수학적으로 설명하고, 오믹스(omics) 데이터에 적용하는 방법을 PyTorch 예제 코드와 함께 다룬다. 바이오인포매틱스 연구자가 생성 모델을 이해하고 활용하는 데 도움이 되기를 바란다.
논문 정보 Title: Current landscape of plasma proteomics from technical innovations to biological insights and biomarker discovery Authors: Douglas Y. Kirsher, Shreya Chand, Aron Phong, Bich Nguyen, Balazs G. Szoke,...
논문 정보 Title: AI-driven toolset for IPF and aging research associates lung fibrosis with accelerated aging Authors: Fedor Galkin, Shan Chen, Alex Aliper, Alex Zhavoronkov, Feng Ren Affiliation: Insilico Medicine...
논문 정보 Title: scDiffusion: conditional generation of high-quality single-cell data using diffusion model Authors: Erpai Luo, Minsheng Hao, Lei Wei, Xuegong Zhang Affiliation: MOE Key Lab of Bioinformatics, Tsinghua University,...
논문 정보 Title: Predicting transcriptional responses to novel chemical perturbations using deep generative model for drug discovery Authors: Xiaoning Qi, Lianhe Zhao, Chenyu Tian, Yueyue Li, Zhen-Lin Chen, Peipei Huo,...